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Machine learning models trained on network pharmacology data can predict which herbal combinations are most likely to act synergistically on complex diseases like IBD

Ferry ST, Dahners LE, Afshari HM, Weinhold PS (2007) The effects of common anti-inflammatory drugs on the healing rat patellar tendon

Calculli, G

A 2014 mouse study found that NAC and vitamin E accelerated lung tumor progression and reduced survival.41 A 2015 melanoma mouse study found that NAC increased lymph node metastases in mice with malignant melanoma.42 A 2019 mouse study reported that NAC protected against emphysema-related lung damage but also induced lung adenocarcinoma in some mice.43 And a 2021 hepatocellular carcinoma study found that antioxidant supplements including NAC promoted tumor formation, growth, and drug resistance in experimental models by reducing intracellular ROS.3 Newer human data add another layer of complexity

Pina F, Petrov V, Laia CAT (2012) Photochromism of flavylium systems