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Repaglinide: a review of its therapeutic use in type 2 diabetes mellitus

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Compared to acute patients, we noted 495 metabolites were significantly reduced but 167 metabolites were elevated in the plasma of LC patients ( Figure 2I )

Exendin-4 (10 g/kg) treated SD rats by subcutaneous injection for 75 days, reduced body weight by approximately 30%, significantly reduced insulin, adiponectin, and leptin levels, but caused pancreatic acinar inflammation and pus toxicosis [7]