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The combination of a monoamine oxidase inhibitor (MAOI), in particular MAO-A inhibitors that preferentially inhibit the metabolism of 5-HT, with serotonergic drugs is especially dangerous, and may lead to the most severe form of the syndrome, and occasionally death

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The analysis found no significant association between specific GLP-1 RAs and androgenetic alopecia, though semaglutide showed a potential trend toward increased hair loss