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They add to cortisols metabolic actions by increasing glucagon secretion and ketogenesis in the liver as well as reabsorption of ketone bodies in the kidney (30) and their side effect of genitourinary infections may be especially disadvantageous in patients with Cushings syndrome who are already at an increased risk of infection

Statements Author contributions MC: Writingoriginal draft, Conceptualization

The three mouse models were SAMP-1 female mice with accelerated aging, wild rats, SAMR-1, and SHR (both female mice)

Yet, they're still tired, still brain-foggy, and coming in wondering, "Is it something else?" But when we do labs and put them on injections, they can notice the change almost immediately

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