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Practical takeaway: Sexual effects typically appear within hours of the first dose

J endocrinological investigation

The usual move is dropping back to the dose you tolerated, giving your body more time, then trying the increase again later, or simply staying where you are if it's working

10.1007/s13311-020-00862-1 Neurotherapeutics 22 MeinN.von StackelbergN.WickelJ.GeisC.ChungH

The effects of gut-derived GLP-1 secretion are considered to be more significant in preventing weight gain rather than directly inducing weight loss, based on findings from animal studies on GLP-1 releasers including gastrointestinal distention [53] and d-allulose [54]