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Moreover, our experiments further verified the role of Nrf2 by using Nrf2-shRNA, Nrf2 agonists, antioxidant and Nrf2 knockout mice, confirming that the protective effects of AZI on CS-induced airway epithelial barrier dysfunction primarily depends on the activation of Nrf2/GCL/GSH signaling pathway

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(the narrator), George, and Harris, along with their dog Montmorency, who decide a two-week boating holiday up the River Thames from Kingston to Oxford will cure their perceived ailments and the stresses of city life

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