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Specifically, we suggest that the benzyl portion of the isobenzopyrrole-1,3-dione moiety of CP17 might be modified to provide groups able to make polar or charge interactions with the carbonyl oxygen of VP1-Ile89 or the carboxylate of the sidechain of VP1 Asp114 (Fig

Approximately 0.15% of the molecular oxygen consumed by mitochondria is reduced to superoxide anion

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