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It comes from a 2010 meta-analysis of Social Relationships and Mortality Risk (see Figure), which benchmarked the size of the effect that lacking social connection has on risk for premature mortality against the effect of other known risk factors, including smoking

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Association between tobacco plain packaging and Quitline calls: a population-based, interrupted time-series analysis

Initially crafted as a custom solution for military personnel, the overwhelming demand and positive feedback led us to develop a more accessible and refined version through state-of-the-art injection molding techniques

It also disguises a persistent problem: tobacco is not an equal opportunity killer, and many communities have not experienced the same reduction in tobacco use