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Users remain on therapy for many months or years they need repeated lab checks, dose titration, short interval follow-ups and tight hand-offs between prescriber and pharmacy

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71 Furthermore, GLP-1RA has been investigated for its potential to reduce the risk of cardiovascular events in patients with or without diabetes

doi: 10.1007/S13530-025-00264-W 88

reported that astrocyte ablation in chronic experimental autoimmune encephalomyelitis ameliorates pathology, whereas acute-phase ablation worsens disease, illustrating a time-dependent dual role 37