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Taunton J, Hassig CA, Schreiber SL

For example, once vitamin C has neutralized a free radical, it becomes inactive

Studies indicate that activation of TLR2/3/4/5 triggers the NF-B/NLRP3 pathway and the PI3K/Akt/mTORC1 signaling pathway, leading to microglial activation, neuroinflammation, and neuronal damage (147, 148)

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The 2-Cys PRXs operate through the formation of a homodimer, in which a disulfide bond connects a peroxidatic Cys (C P ) 175 from one monomer and is connected to the resolving Cys located on the second monomer