Alcohol-associated PAGln production and cardiovascular dysfunction are transmissible traits To address the relative contribution of alcohol-induced gut microbial reorganization towards increased PAGln levels and subsequent cardiovascular dysfunction, we performed microbial transplantation of gut commensals from PF and AF mice into nave mice using a previously reported protocol with modifications as described (Fig
Dadiani, M., Kalchenko, V., Yosepovich, A., Margalit, R., Hassid, Y., Degani, H., et al
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With decreased gastric emptying and increased satiety, a common pharmacological effect observed when conducting these studies is a decrease in food consumption and body weight loss
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