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Reactive oxygen species and cellular defense system
Systemic effects less commonly include mild dizziness or lightheadedness (may be copper-related), temporary nausea or headache (typically resolves within hours), mild fatigue (rare, reported with higher doses), and transient flu-like symptoms (very rare, may relate to systemic inflammatory response)
They described insurance denials, pharmacy shortages, and punishing out-of-pocket costs
These pharmacies can create medications tailored to specific dosages, which can be helpful if a patient needs a very gradual dose increase to avoid the side effects often seen when combining medications with topiramate
Henikoff S, Haughn GW, Calvo JM, Wallace JC
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