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Future investigations should explicitly test causality by systematically inhibiting individual components of the gutimmunebrain axis to establish direct therapeutic mechanisms

doi: 10.1016/S0190-9622(08)80969-3 [61] Frangogiannis NG, Boridy I, Mazhar M et al

(Biotech Peptides) The SASP incites local chronic inflammation, tissue dysfunction, matrix breakdown, fibrosis, and impairs regeneration

Effect of Tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial

Nevertheless, research findings across these diseases are inconsistent, highlighting the complexity of host-microbiota interactions (172)