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Female partner underwent comprehensive diagnostic evaluation.Her hormonal profile, including anti-Mllerian hormone, follicle-stimulating hormone (FSH), and thyroid function, were all within the reference ranges

For many, taking drugs like Ozempic has been about more than just getting thinner

However, emerging evidence suggests that the actions of GLP-1 are not limited to glycemic control

Most interesting was the induction not only of the membrane GLP-1R with treatment, but also the significant upregulation of nuclear and membrane progesterone receptorsPR and PGRMC1/2, respectivelyindicating a potential positive feedback loop between semaglutide and progestins such as levonorgestrel

This potentiation is associated with their ability to inhibit efflux pumps 134