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And the combination of delayed gastric emptying on top with slow colonic transit below creates a compression effect that makes bloating feel worse than either issue would on its own
This can undermine motivation, trigger body image concerns, and lead to premature discontinuation of a medication that is otherwise working well
Understanding the expected timeline for semaglutide effects helps you frame these questions
Research indicates that gastrointestinal symptoms, including bloating, are substantially reduced after approximately 20 weeks of consistent use
If constipation occurs alongside bloating, over-the-counter osmotic laxatives (such as polyethylene glycol) or stool softeners may be helpful, but should be discussed with your healthcare provider first
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