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In parallel, triple agonists simultaneously targeting GIP, GLP-1, and GCG receptors are also under investigation, aiming to deliver greater WL and metabolic improvements than mono- or dual-agonists

(5) Improving male fertility: L-carnitine has been found to improve sperm quality and increase testosterone levels in men

Skin infection induced sepsis is the major cause of death [25]

Mostly similar, but tirzepatide has lower constipation rates (9% vs 24%) and modestly lower nausea rates (31% vs 44% at equivalent weight-loss doses)

supplemented with 10% fetal bovine serum (Cultilab), 100 IU/ml of penicillin, and 100 g/ml of streptomycin (Sigma-Aldrich, Saint Louis, MO, USA)