10.1080/07391102.2017.1401003 J
This peptide is derived from the polypeptide epithalamin that is produced in the thymus gland
Conclusions Many patients with HT, even in the euthyroid state, have high oxidative stress, excess body weight and metabolic disorders
This dual insult exacerbates endothelial dysfunction and promotes pathological vascular remodeling and sclerosis, creating a vicious cycle that elevates blood pressure [198, 218]
The analogues were synthesised via Fmoc-solid-phase peptide synthesis, and they were characterised using reverse-phase high-performance liquid chromatography (RP-HPLC), electrospray ionisation mass spectrometry (ESI-MS), Fourier-transform infrared spectroscopy (FTIR), and nuclear magnetic resonance (NMR) spectroscopy