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Hormones (Athens)

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We developed a rapid endoplasmic reticulum (ER) immunoprecipitation strategy to isolate ER fractions and, by using it, identified SLC33A1 as an ER transporter that exports oxidized glutathione

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Keap-1 contains several cysteine residues, among them, three were extensively studied and confirmed as redox sensitizing-cysteine (Cys151 in BTB domain, Cys273 and Cys288 in IVR domain) (Yamamoto et al., 2008)