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As research continues to unravel the intricate interplay of metabolic pathways, GLP-1 agonists stand poised to redefine the landscape of obesity treatment, empowering individuals to embark on a transformative journey towards improved health and well-being

doi:10.1016/0005-2736(82)90190-0

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In the SURMOUNT-1 trial, tirzepatide 15 mg produced a mean weight reduction of 22.5% over 72 weeks in adults without diabetes, highlighting the potential value of multi-receptor metabolic therapy

However, the Food and Drug Administration (FDA) guidelines do not require the assessment of muscle quality or volume in clinical trials assessing the efficacy of GLP-1 drugs for weight loss