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"There's an assumption that nicotine dependence is an acute disease that can be treated with short-term therapy," says Caryn Lerman, one of the study's authors and the director of the Tobacco Use Research Center at the University of Pennsylvania

Using the high-quality mzCloud database constructed from standards in combination with the mzVault and Mass List databases, molecular feature peaks were matched and identified, enabling the identification of as many metabolites in the biological system as possible, thus providing a comprehensive reflection of the total metabolite information

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In the 1800s, a company Bugler announced new shipments of tobacco