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Animal model studies consistently demonstrated that semaglutide can significantly alter gut microbiota, suggesting that part of semaglutides metabolic benefit may derive from its capacity to modulate inflammation via gut-immune-microbiota interactions and to correct dysbiosis induced by high-fat diets [82, 84]

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Diet-induced obese (DIO) mice and rats fed a high-fat diet received semaglutide, administered subchronically, and the effects on food intake and BW were evaluated

Keeping your body hydrated will go a long way toward enhancing your weight loss results