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Human RCTs have suggested that creatine (monohydrate form) could revitalize cellular bioenergetics, neuro-metabolism, and immune function, thereby may provide a multifunctional benefit in recovery of PASC with MS/CFS complications 546,547

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It thus involves well-regulated mechanisms mainly executed by macrophages in the whole body [222]

In humans, according to meta-analyses, NAC is able to decrease the exacerbation rate in patients with COPD by more than 20% [7375]