Sermorelin is not a standard or licensed treatment for adult growth hormone deficiency within UK clinical practice
Details of saliva collection are described in our paper ( 2.4 Markers of the kynurenine and serotonin pathways, neopterin, biopterin, and creatinine in urine From an ethical standpoint, we opted for non-invasively collected urine (in contrast to invasive blood collection) to determine TRP degradation metabolites, considering the observed concordance between peripheral levels and levels in the central nervous system ( Levels of urine metabolites (creatinine, TRP, KYN, 5-HTP, SER, 5-HIAA, NEO, BIO) were determined using reversed-phase high-performance liquid chromatography (RP-HPLC system, Prominence 20A, Shimadzu Corporation, Japan) equipped with UV-VIS absorption (module SPD-20A) and fluorescence (module RF-10AXL) detectors
Improved sleep quality is typically the first benefit patients notice, usually within the first one to two weeks
Could it trigger a flare-up or exacerbate the condition
The formulation includes hyaluronic acid for hydration, antioxidants to protect against ageing and amino acids to improve skin texture
