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Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells

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However, OCTN1 and OCTN2 both have narrower substrate specificity compared to polyspecific OCTs and OATs, and uptake assays performed with a large panel of drugs suggest that OCTN2 is not a general drug transporter 3,12,17,18

The titration schedule increasing the dose gradually allows incretin hormones to stabilize appetite and improve glucose dependent insulinotropic polypeptide activity