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(2007) find that counterfeit cigarettes can have as much as seven times the lead of legitimate brands, and close to three times as much thallium.[13] Other sources report finding insect eggs, dead flies, mold, and human feces in counterfeit cigarettes.[14] As was the case during the prohibition of alcohol in the United States during the 1920s, increased enforcement has not yielded beneficial results for decreasing the prevalence of bootlegging because the profit margins are so large and the distribution networks are growing more sophisticated

10.1038/s41580-021-00433-y [DOI] [PubMed] [Google Scholar] Boyman L., Karbowski M., Lederer W

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based on these correlation rates, it is estimated that the approximate number of mutations accumulated in a normal cell of each tissue due to smoking a pack of cigarettes per day for a year is 150, particularly in the lungs.12 A recent study showed that smoking duration alone reportedly provides stronger risk estimates of COPD than the composite index of pack-years.13 However, it remains unknown whether smoking duration can also replace pack-years for predicting smoking-related oncogenic mutations in non-small cell lung cancer (NSCLC)