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Chronic Constipation and Diarrhea Slowed-down peristalsis due to the nicotine effect on smooth muscle cells found within walls of the intestines may lead to prolonged transit time, hence chronic constipation while increased activity can cause rapid passing of food leading to watery stools thus diarrhea

Therefore, understanding these connections allows certain areas to be stimulated and recorded, to monitor neurotransmitter release and receptor response in particular regions of the brain

One feature I do wish it had however, was an easily removable bowl that kind of sat on the base, instead of being attached to it