glp-1 liver disease fatty Multiple target tissue effects of analogues on non-alcoholic (NAFLD) and non-alcoholic steatohepatitis (NASH) The Emerging Role of Glucagon-Like – GLP-1 Therapies Reduce Risk of

doi: 10.1038/s41579-018-0089-x 21 LundmarkAHuYOOHussMJohannsenGAnderssonAFYucel-LindbergT

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GE2 treatment increases neurogenesis in the dorsal hippocampus depending on sex and diet WD reduced the density of DCX-expressing cells compared to SD ( p = 0.024, Cohens d = 1.309), but only in males, and GE2 treatment normalized the density of DCX-expressing cells under a WD in males ( p = 0.008, Cohens d = 4.023

Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study