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These exerkines act through autocrine, paracrine, or endocrine mechanisms to mediate inter-organ communication, playing essential roles in regulating nervous system function, attenuating neuroinflammation, and promoting neural repair ( 2+ , lactate dehydrogenase (LDH), MDA, and lipid ROS, inhibited neuronal ferroptosis and lipid peroxidation, thereby ameliorating oxygen-glucose deprivation and reoxygenation (OGD/R)-induced neuronal injury

Mild side effects are possible, but most users tolerate it well under proper supervision

doi:10.1126/scitranslmed.3001127

It corresponds directly with the visible and measurable decline in tissue repair capacity that most people associate with aging: slower wound healing, reduced skin elasticity, thinning hair, and longer recovery times after physical stress

doi: 10.1080/09513590.2023.2166483 166 TangHJiangXHuaYLiHZhuCHaoXet al