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[PMC free article: PMC5773841] [PubMed: 29182497] Incidence and Mortality Oral cavity and oropharynx cancers From 2017 to 2021, the estimated age-adjusted incidence rate for cancers of the oral cavity and oropharynx in the United States was 11.5 cases per 100,000 persons per year.[1] Cancers of the tongue, oropharynx, and tonsil comprise the majority of cases (30% tongue and 24% oropharynx and tonsil)