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Siegel PM, Massagu J

Effect sizes were calculated using standardized mean differences between conditions for the primary outcome (that is, Glx/tNAA change from baseline) and any relevant changes in day 1 clinical measure scores

It can actually start a cycle where the nerve releases substances that activate the mast cells, releasing mediators that activate the nerve

As water content decreases, the relative concentration of these compounds increases, producing a stronger ammonia-like smell

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