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The micro-organisms in the rumen convert dietary cobalt into vitamin B12 What are the effects of vitamin B12 deficiency: Vitamin B12 deficiency in sheep can cause a number of clinical signs including loss of appetite, decreased growth rates, weight loss, watery ocular discharge and anaemia

Nature 2011;477:1718

I did notice a decrease in appetite and no pms symptoms this month

Its also worth noting that individuals may experience different symptoms or levels of improvement from B12 injections, depending on their health status and B12 levels before injection

Since semaglutide is typically injected once weekly and B12 is given monthly or taken daily, they operate on different timelines