In mice with T cell-specific deletion of Gpx4 , microbes-specific CD8 + and CD4 + T cells were unable to proliferate normally meanwhile exhibiting enhanced sensitivity towards viral and parasitic infections
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Topotecan, a topoisomerase I inhibitor, is active in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia
doi: 10.1186/1465-9921-7-124