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Lancet Neurol 20(10):795820

GHK-CU works to protect the damaged tissue, lower inflammation, and replace scarred tissue with healthy tissue

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Teams are working on conjugating LR3 to muscle-specific ligands (integrins, dystroglycan) or neuronal ones (cell-penetrating peptides, blood-brain barrier targeting via transferrin receptor transcytosis) to concentrate trophic action where desired while limiting potentially deleterious systemic effects (hypoglycemia, uncontrolled mitogenesis)