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Treatment persistence has improved compared to earlier GLP-1 formulations, though discontinuation rates remain significant, often due to gastrointestinal side effects or cost concerns

Nonetheless, the interpretation of current data is limited by detection and prescription biases in observational studies as well as insufficient follow-up and number of events in randomized trials

Recent research reveals that GHK-Cu influences over 4,000 genes, many involved in tissue repair and regeneration

Diabet Med 29(8):e205e210

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