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Amyloidosis can be confirmed with additional histochemical staining (Congo red) where it shows pink-red staining and apple green birefringence under polarized light (Vowles and Francis 2002

Discussion Although numerous studies have shown that cardiac energy metabolism is altered in pathological cardiac remodeling and that the resulting myocardial energy deficit can lead to further HF, there is minimal research on therapeutic targets and drugs based on this energy shift 2,38

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