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Epitalon and pineal-immune connections Epitalon is a tetrapeptide that acts on the pineal gland to promote melatonin production

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As part of this pathological process, hepatic lipid accumulation and immune cell infiltration trigger the sustained release of proinflammatory cytokines and chemokines, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-), driving a systemic inflammatory response [26, 29]