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Zhao XY, Li SS, He YX, Yan LJ, Lv F, Liang QM et al (2023) SGLT2 inhibitors alleviated podocyte damage in lupus nephritis by decreasing inflammation and enhancing autophagy

10.1126/scitranslmed.aar5280 Sci

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Bao et al (60) found downregulation of the ferroptosis regulator GPX4 in both Fpnfl/fl/NEXcre (NEX-Cre mice were mated with Fpn-floxed (Fpnfl/fl) mice to generate conditional Fpnfl/fl/NEXcre mice.) and APPswe/PS1dE9 (Carrying genetically modified mice with AD-related mutations: a chimeric mouse/human APP with the Swedish mutation and human PSEN1 lacking exon 9) mouse models compared with controls

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