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The system used consisted of UltiMate 3000 coupled with an Exploris 480 mass spectrometer (Thermo Fisher Scientific) equipped with a Nanospray Flex interface operated in a positive ion mode

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As a fixed-dose combination, CagriSema was assessed in two phase 3 studies (REDEFINE 1 and 2), resulting in significant and clinically relevant reductions in body weight compared with placebo in adults with overweight or obesity, with [8] or without type 2 diabetes [9]

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When inflammation is reduced, the symptoms of AD such as redness, dryness and itchiness of the skin will be reduced which subsequently minimizes pain and swelling