Metals present in the aerosol (e.g., copper, zinc and cobalt) have been shown to modulate drug transport at a posttranscriptional level 61 , as well as to contribute to increased ROS levels 62
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In the mid-2000s, many countries (including Australia, the US, and the EU) banned the use of terms like "Lights," "Mild," or "Low-Tar," arguing that these labels could mislead consumers into thinking the products were "healthier." To comply with these laws while keeping the product recognizable, Philip Morris rebranded: Marlboro Lights became Marlboro Gold
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