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It depends on how much nicotine you used and your body's reaction

Brody AL, Mandelkern MA, Costello MR, Abrams AL, Scheibal D, Farahi J et al (2009)

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The hearings also included testimonies from two high school students and their mothers about a class presentation from a JUUL representative, supposedly focusing on addiction and wellness, who said JUUL was "totally safe." Marketing programs aimed at other groups including Native Americans and veterans were also uncovered during the hearings