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Researchers found people who used e-cigarettes may have a 19% increased risk of heart failure.

Nicotine may cause constrictions in blood vessels to the umbilical cord and uterus, which decreases the amount of oxygen available to the fetus

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However, among never smokers who did not smoke regular cigarettes, the difference in the occurrence of metabolic syndrome became apparent earlier, after 8 months of follow-up (Figure 2)