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Indeed, experimental analysis showed that introduction of doxorubicin into physiologically relevant pH media yielded a concentration-dependent oxygen consumption profile, revealing free (non-metal catalysed) auto-oxidation (Fig

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Osmotic vs stimulant laxatives (OTC options) First-line pharmacologic option: Polyethylene glycol (PEG 3350) is recommended by gastroenterology guidelines because it increases stool water content, improves stool frequency, and is generally well tolerated for ongoing use. Alternative osmotic option: Magnesium oxide may help some patients and is conditionally recommended in gastroenterology society guidance

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