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Multiple clinical studies have shown that integrating metabolic modulation with immunotherapy, chemotherapy, or targeted agents can significantly improve outcomes (Table 2)

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According to this analysis, pMMR patients in the Lynparza and Imfinzi group showed a 43% reduction in the risk of disease progression or death compared to the control group (median 15.0 months versus 9.7 months, hazard ratio [HR] 0.57

Sun Z, Wu J, Bi Q, Wang W

We thus tested the hypothesis that hyperphagic responses observed after PPG NTS neuronal ablation are specifically due to a delay in meal termination, to establish a bona fide role for PPG NTS neurons in the process of satiation