Journal of Pharmaceutical Research Year: 2026, Volume: 25, Issue: 1, Pages: 16-19 Review Article Sagarika Basavaraj 1* , Aparna Chincholkar 2 1 Junior Resident, Department of Pharmacology, MAEER'S MIT Pune's MIMER Medical College and Dr BSTR Hospital, Talegaon Dhabade, Pune- 410507, Maharashtra, India 2 Professor, Department of Pharmacology, MAEER'S MIT Pune's MIMER Medical College and Dr BSTR Hospital, Talegaon Dhabade, Pune- 410507, Maharashtra, India *Corresponding Author Sagarika Basavaraj Email: [email protected] Obesity is a chronic, relapsing disease associated with significant cardiometabolic, mechanical, and psychological consequences
A pro tip
It often requires long-term treatment, sometimes for life
Through three precise molecular modifications to the natural GLP-1 sequence, researchers created a peptide that resists enzymatic breakdown, binds to albumin in the bloodstream, and maintains active receptor signaling for approximately 165 hours
It was concluded that there was a good correlation between PK and the length of the fatty acid when using linear mono-acids
