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NAD+ is required for ATP production, and topping up a declining pool is the rationale [1]

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When cyano B12 does absorb, it converts to hydroxo B12 (hopefully discarding the cyanide in the process)

Research published in peptide patent literature from Diagen indicates the arginate form can achieve oral bioavailability exceeding 90%, compared to less than 3% for the acetate form

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