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In June 2026 the MHRA approved the Wegovy pill (oral semaglutide 25 mg), the first oral GLP-1 medicine licensed in the UK for weight loss

Retatrutide data comes from 48 week trials while Tirzepatide data extends to 72 weeks

Weight loss is considered a side effect of metformin, and its sometimes prescribed off-label for weight management purposes in specific instances

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Social activities might be avoided due to fear of judgment or panic attacks