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Central sensitization refers to a phenomenon in which the central nervous system becomes hypersensitive to pain signals, leading to the perception of pain even without a noxious stimulus 8,9
Causes include an overload of precurors, viral hepatitis, mensutration, or temporary childhood circumstances
PubMed 22962027 TB-4 Phase 1 human safety first-in-human randomized, double-blind, single- and multiple-dose Phase 1 of recombinant human thymosin 4 in healthy volunteers, no serious adverse events: PubMed 34346165
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