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Models should prioritize clinically interpretable structures (e.g., tree models, Bayesian networks, or explainable ensemble models) to facilitate integration into shared decision-making in the clinic

Apply a moderate amount to the entire body or desired areas

SGLT2 inhibitor-induced weight loss results primarily from a decrease in fat mass, including reductions in visceral and subcutaneous adipose tissue (139)

Several indirect mechanisms may explain why some individuals experience increased thirst while taking GLP-1 medications, even though thirst is not a direct pharmacologic effect of these agents

A monoclonal antibody called bimagrumab is currently in Phase 2 clinical trials at Eli Lilly