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10.1016/j.neuropharm.2018.03.041 [DOI] [PubMed] [Google Scholar] Ferr S, Orr M, Guitart X (2013) Paraxanthine: connecting caffeine to nitric oxide neurotransmission

[1] [4] Do not rely solely on sublingual supplements if you have neurological symptomsthese require urgent medical evaluation and may necessitate intramuscular B12 therapy to prevent irreversible nerve damage