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Its signaling cascade is centered around human Caspase-1, Caspase-4, and Caspase-5, or murine Caspase-11 (44)

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In addition, GLP-1RAs could also increase energy consumption

Canonical AREs consist of a repeat of a 5TGTTCT3 hexamer, separated by three base pairs, which resembles the DNA recognition motifs for other NRs, such as GR [49]